Regenerative melt-in cream

A good cream is one that addresses your skin’s actual biological needs, not just its visible signs. Before choosing a texture, consider the active ingredients: are they present in sufficient concentrations? Has their effectiveness been tested on living tissue?

At LBA, two sizes are available depending on the desired intensity: the Regenerative melt-in cream for deep daily regeneration, and the Regenerative serum in cream for skin seeking the highest concentration of active ingredients. Both are based on NEO-REGEN® technology and meet the same clinical validation standards.

Among the most scientifically well-documented ingredients are retinol, niacinamide, hyaluronic acid, and ceramides. Our formulas incorporate niacinamide and seven types of ceramides, while going a step further with proprietary biotechnological active ingredients that conventional research has not yet explored to this extent.

White lily and peony stem cells, Baulieu water mineralized by basalt rock, and ectoine: their efficacy is being evaluated on human skin organoids in collaboration with Prof. Jean-Marc Lemaître, a research director atInserm. The goal is not to validate a claim but to understand what is actually happening in the tissues.

Niacinamide, or vitamin B3, is one of the most well-documented active ingredients in cosmetics. It supports ceramide synthesis, strengthens the skin barrier, evens out skin tone, and reduces the appearance of pores. It also has antioxidant and anti-inflammatory properties, making it a particularly versatile active ingredients .

In our formulas, niacinamide is not used on its own; rather, it is part of a synergistic blend of biotechnological active ingredients designed to address the underlying mechanisms of skin aging, not just its visible effects.

Ingredients with scientifically proven anti-wrinkle effects include retinol, signaling peptides, niacinamide, and ceramides. Research on plant stem cells now plant stem cells a complementary approach: rather than targeting the symptom, it focuses on the cells’ ability to maintain tissue structure.

LBA’s NEO-REGEN® technology has demonstrated a measurable effect on 136 genes involved in skin regeneration, with clinical results showing a 21% reduction in wrinkles and a 53% increase in firmness at three months, as measured on living tissue.

A serum delivers a high concentration of active ingredients to the deeper layers of the skin. A cream strengthens the skin barrier and maintains moisture. The two perform complementary biological functions.

At LBA, we have moved beyond this dichotomy with the Regenerative serum in cream : a hybrid texture with a lamellar structure, designed to combine the rapid absorption of a serum with the nourishing action of a cream. Used alone or in combination with the Fondante Cream, it forms a complete regenerative regimen.

Culturing in bioreactors makes it possible to propagate plant stem cells in a strictly controlled environment—free from climatic variations, pesticides, and large-scale extraction from ecosystems.

The benefits are numerous: complete traceability, a stable and reproducible composition, superior purity, and a reduced environmental impact. At LBA, this is the process we use for all of our plant-based active ingredients. A tiny fragment of a plant from Domaine de Baulieu to generate millions of stem cells with their regenerative properties intact.

It is part of a longevity approach —which is different. The anti-aging approach is corrective: it targets the visible signs of aging. The regenerative approach is preventive and structural: it supports the skin’s ability to renew itself and maintain its density, radiance, and vitality over time.

At LBA, we don’t fight aging. We help the skin stay as beautiful as it can be.

As soon as the skin needs support to combat environmental stress or the first signs of cellular aging—usually starting in one’s thirties, though sometimes earlier, depending on skin type and lifestyle.

Regenerative skincare isn't meant for a specific age group. It's designed for skin that seeks to maintain its vitality over time.

Our formulas are designed to be biocompatible—that is, formulated to work in harmony with the skin’s natural physiology, free from disruptive ingredients, silicones, and PEGs. This approach makes them particularly suitable for demanding and sensitive skin.

If you have any questions, our Le Cercle concierge service is available to provide personalized advice before you adopt a new routine.

Yes, our products are designed for daily use, morning and night. The skin regenerates mainly at night, making it the ideal time to apply the Cream Serum. In the morning, the Melting Cream prepares and protects the skin barrier for the day ahead.

This is the core principle of our formulation approach. Our biomimetic lamellar structures replicatethe natural organization of skin lipids —an architecture modeled after the epidermal barrier, which allows active ingredients to penetrate exactly where they need to act, without disrupting the skin’s natural balance.

Formulating products that are gentle on the skin is not a marketing choice. It is a biological necessity.